5-HT1D receptor, 5-HT1D receptor agonist, 5-HT1E receptor

5-HT1D mai karɓa: 5-hydroxytryptamine (serotonin) mai karɓar 1D , wanda aka fi sani da HTR1D , mai karɓar 5-HT ne, amma kuma yana nuna kwayar halittar mutum da ke sanya shi. 5-HT 1D yana aiki akan tsarin juyayi na tsakiya, kuma yana shafar motsi da damuwa. Hakanan yana haifar da jijiyoyin bugun jini a cikin kwakwalwa.
5-HT1D agonist mai karɓa: 5-HT 1D agonists masu karɓar maganin ƙwayoyi ne don maganin ƙaura. Sun hada da: Masu fassara Ergotamine Dihydroergotamine, wanda ya samo asali daga tsohon Alniditan
5-HT1E mai karɓa: 5-hydroxytryptamine (serotonin) 1E mai karɓa (5-HT 1E ) wani ɗan adam ne mai cikakken furotin G-protein haɗe da mai karɓar na 5-HT1 dangin mai karɓa. An nuna asalin ɗan adam a matsayin HTR1E .
5-HT1E mai karɓa: 5-hydroxytryptamine (serotonin) 1E mai karɓa (5-HT 1E ) wani ɗan adam ne mai cikakken furotin G-protein haɗe da mai karɓar na 5-HT1 dangin mai karɓa. An nuna asalin ɗan adam a matsayin HTR1E .
5-HT1F mai karɓa: 5-hydroxytryptamine (serotonin) mai karɓar 1F , wanda aka fi sani da HTR1F furotin ne mai karɓar 5-HT 1 kuma yana nuna kwayar halittar mutum da ke sanya shi.
5-HT1F mai karɓa: 5-hydroxytryptamine (serotonin) mai karɓar 1F , wanda aka fi sani da HTR1F furotin ne mai karɓar 5-HT 1 kuma yana nuna kwayar halittar mutum da ke sanya shi.
Serotonin agonist mai karɓa: Agonist mai karɓa na serotonin shine agonist na ɗaya ko fiye masu karɓar maganin serotonin. Suna kunna masu karɓar maganin serotonin ta hanyar kama da na serotonin, neurotransmitter da hormone da haɗarin haɗarin masu karɓar maganin serotonin.
5-HT mai karɓa: Masu karɓar 5-HT, masu karɓar 5-hydroxytryptamine , ko masu karɓar serotonin , ƙungiya ce ta mai karɓar furotin na G da kuma tashoshin ion da ke cikin jijiyoyin da ke cikin tsakiya da tsarin jijiyoyin jiki. Suna yin sulhuntawa da haɓakawa da hana karɓuwa. Masu karɓar maganin serotonin suna aiki ta hanyar serotonin neurotransmitter, wanda ke aiki azaman ligand ɗin su na halitta.
5-HT1 mai karɓa: Masu karɓar 5-HT 1 ƙungiya ce ta 5-HT serotonin masu karɓa waɗanda ke ɗaure da kwayar cutar kwayar cutar kwayar cutar serotonin (wanda aka fi sani da 5-hydroxytryptamine, ko 5-HT). Fungiyar 5-HT 1 ta ƙunshi masu karɓar haɗin G guda biyar (GPCRs) waɗanda aka haɗu da G i / G o kuma yin sulhu mai hana karɓuwa, ciki har da 5-HT 1A , 5-HT 1B , 5-HT 1D , 5-HT 1E , da 5-HT 1F . Babu mai karɓar 5-HT 1C , kamar yadda aka sake sanya shi azaman mai karɓar 5-HT 2C . Don ƙarin bayani, da fatan za a duba manyan abubuwan da aka keɓance na ƙananan ƙananan mutane:
5-HT2 mai karɓa: Masu karɓar 5-HT 2 ƙungiya ce ta masu karɓar 5-HT waɗanda ke ɗauke da kwayar cutar kwayar cutar serotonin (5-hydroxytryptamine, 5-HT). Fungiyar 5-HT 2 ta ƙunshi masu karɓar haɗin G guda uku (GPCRs) waɗanda aka haɗa zuwa G q / G 11 da kuma sasantawa ta hanyar motsa jiki, ciki har da 5-HT 2A , 5-HT 2B , da 5-HT 2C . Don ƙarin bayani, da fatan za a duba manyan abubuwan da aka keɓance na ƙananan ƙananan mutane:
5-HT2A mai karɓa: Mai karɓa na 5-HT 2A wani nau'i ne na mai karɓar 5-HT 2 wanda yake cikin dangin mai karɓar serotonin kuma yana da mai karɓar sinadarin G guda biyu (GPCR). Mai karɓar 5-HT 2A shine mai karɓar ƙwayar salula. 5-HT takaice ne ga 5-hydroxy-tryptamine, wanda shine serotonin. Wannan shine babban nau'in mai karɓar mai karɓar rashi tsakanin GPCRs don serotonin, kodayake 5-HT 2A na iya samun tasiri mai hanawa a wasu yankuna kamar kwalliyar gani da gaɓoɓin farji. An fara lura da wannan mai karɓa ne saboda mahimmancinsa azaman makamar magungunan serotonergic psychedelic kamar LSD da psilocybin namomin kaza. Daga baya ya dawo cikin martaba saboda an kuma gano yana matsakaita, a kalla wani bangare, aikin da yawa daga magungunan da ke cutar da tabin hankali, musamman wadanda ba su da illa.
5-HT2A mai karɓa: Mai karɓa na 5-HT 2A wani nau'i ne na mai karɓar 5-HT 2 wanda yake cikin dangin mai karɓar serotonin kuma yana da mai karɓar sinadarin G guda biyu (GPCR). Mai karɓar 5-HT 2A shine mai karɓar ƙwayar salula. 5-HT takaice ne ga 5-hydroxy-tryptamine, wanda shine serotonin. Wannan shine babban nau'in mai karɓar mai karɓar rashi tsakanin GPCRs don serotonin, kodayake 5-HT 2A na iya samun tasiri mai hanawa a wasu yankuna kamar kwalliyar gani da gaɓoɓin farji. An fara lura da wannan mai karɓa ne saboda mahimmancinsa azaman makamar magungunan serotonergic psychedelic kamar LSD da psilocybin namomin kaza. Daga baya ya dawo cikin martaba saboda an kuma gano yana matsakaita, a kalla wani bangare, aikin da yawa daga magungunan da ke cutar da tabin hankali, musamman wadanda ba su da illa.
5-HT2A mai karɓa: Mai karɓa na 5-HT 2A wani nau'i ne na mai karɓar 5-HT 2 wanda yake cikin dangin mai karɓar serotonin kuma yana da mai karɓar sinadarin G guda biyu (GPCR). Mai karɓar 5-HT 2A shine mai karɓar ƙwayar salula. 5-HT takaice ne ga 5-hydroxy-tryptamine, wanda shine serotonin. Wannan shine babban nau'in mai karɓar mai karɓar rashi tsakanin GPCRs don serotonin, kodayake 5-HT 2A na iya samun tasiri mai hanawa a wasu yankuna kamar kwalliyar gani da gaɓoɓin farji. An fara lura da wannan mai karɓa ne saboda mahimmancinsa azaman makamar magungunan serotonergic psychedelic kamar LSD da psilocybin namomin kaza. Daga baya ya dawo cikin martaba saboda an kuma gano yana matsakaita, a kalla wani bangare, aikin da yawa daga magungunan da ke cutar da tabin hankali, musamman wadanda ba su da illa.
5-HT2B mai karɓa: 5-Hydroxytryptamine mai karɓar 2B ( 5-HT 2B ) wanda aka fi sani da mai karɓar maganin serotonin 2B furotin ne wanda ke jikin mutum an tsara shi ta kwayar HTR2B . 5-HT 2B memba ne na dangin mai karɓar 5-HT 2 wanda ke ɗaure serotonin na neurotransmitter (5-hydroxytryptamine, 5-HT).
5-HT2B mai karɓa: 5-Hydroxytryptamine mai karɓar 2B ( 5-HT 2B ) wanda aka fi sani da mai karɓar maganin serotonin 2B furotin ne wanda ke jikin mutum an tsara shi ta kwayar HTR2B . 5-HT 2B memba ne na dangin mai karɓar 5-HT 2 wanda ke ɗaure serotonin na neurotransmitter (5-hydroxytryptamine, 5-HT).
5-HT2C mai karɓa: Mai karɓar 5-HT 2C wani nau'in nau'i ne na mai karɓar 5-HT wanda ke ɗauke da kwayar cutar kwayar cutar serotonin (5-hydroxytryptamine, 5-HT). Yana da mai karɓar furotin G guda biyu (GPCR) wanda yake haɗe da G q / G 11 kuma yana yin musayar siginar ne. HTR2C yana nuna tsarin kwayar halittar mutum don mai karɓa, cewa a cikin mutane yana cikin ch chromosome na X. Kamar yadda maza ke da kwaya daya na kwayar halitta kuma a cikin mata daya daga cikin kwafin kwayar halitta guda biyu an danne su, polymorphisms a wannan mai karɓa na iya shafar jinsi biyu zuwa daban.
5-HT2C mai karɓa: Mai karɓar 5-HT 2C wani nau'in nau'i ne na mai karɓar 5-HT wanda ke ɗauke da kwayar cutar kwayar cutar serotonin (5-hydroxytryptamine, 5-HT). Yana da mai karɓar furotin G guda biyu (GPCR) wanda yake haɗe da G q / G 11 kuma yana yin musayar siginar ne. HTR2C yana nuna tsarin kwayar halittar mutum don mai karɓa, cewa a cikin mutane yana cikin ch chromosome na X. Kamar yadda maza ke da kwaya daya na kwayar halitta kuma a cikin mata daya daga cikin kwafin kwayar halitta guda biyu an danne su, polymorphisms a wannan mai karɓa na iya shafar jinsi biyu zuwa daban.
5-HT2C agonist mai karɓa: 5-HT 2C agonists masu karɓar raƙuman ruwa sune rukunin magungunan da ke kunna masu karɓar 5-HT 2C . An bincika su don maganin wasu sharuɗɗa da suka haɗa da kiba, cututtukan ƙwaƙwalwa, lalatawar jima'i da rashin yin fitsari.
5-HT2C agonist mai karɓa: 5-HT 2C agonists masu karɓar raƙuman ruwa sune rukunin magungunan da ke kunna masu karɓar 5-HT 2C . An bincika su don maganin wasu sharuɗɗa da suka haɗa da kiba, cututtukan ƙwaƙwalwa, lalatawar jima'i da rashin yin fitsari.
5-HT2 mai karɓa: Masu karɓar 5-HT 2 ƙungiya ce ta masu karɓar 5-HT waɗanda ke ɗauke da kwayar cutar kwayar cutar serotonin (5-hydroxytryptamine, 5-HT). Fungiyar 5-HT 2 ta ƙunshi masu karɓar haɗin G guda uku (GPCRs) waɗanda aka haɗa zuwa G q / G 11 da kuma sasantawa ta hanyar motsa jiki, ciki har da 5-HT 2A , 5-HT 2B , da 5-HT 2C . Don ƙarin bayani, da fatan za a duba manyan abubuwan da aka keɓance na ƙananan ƙananan mutane:
5-HT2A mai karɓa: Mai karɓa na 5-HT 2A wani nau'i ne na mai karɓar 5-HT 2 wanda yake cikin dangin mai karɓar serotonin kuma yana da mai karɓar sinadarin G guda biyu (GPCR). Mai karɓar 5-HT 2A shine mai karɓar ƙwayar salula. 5-HT takaice ne ga 5-hydroxy-tryptamine, wanda shine serotonin. Wannan shine babban nau'in mai karɓar mai karɓar rashi tsakanin GPCRs don serotonin, kodayake 5-HT 2A na iya samun tasiri mai hanawa a wasu yankuna kamar kwalliyar gani da gaɓoɓin farji. An fara lura da wannan mai karɓa ne saboda mahimmancinsa azaman makamar magungunan serotonergic psychedelic kamar LSD da psilocybin namomin kaza. Daga baya ya dawo cikin martaba saboda an kuma gano yana matsakaita, a kalla wani bangare, aikin da yawa daga magungunan da ke cutar da tabin hankali, musamman wadanda ba su da illa.
5-HT2C agonist mai karɓa: 5-HT 2C agonists masu karɓar raƙuman ruwa sune rukunin magungunan da ke kunna masu karɓar 5-HT 2C . An bincika su don maganin wasu sharuɗɗa da suka haɗa da kiba, cututtukan ƙwaƙwalwa, lalatawar jima'i da rashin yin fitsari.
5-HT3 mai karɓa: Mai karɓa na 5-HT 3 na mamakin gidan Cys-loop ne na tashar tashoshin haɗin gwanon jini (LGICs) sabili da haka ya bambanta da tsari da aiki daga dukkan sauran masu karɓar 5-HT (5-hydroxytryptamine, ko serotonin) waɗanda ke da haɗin G-haɗe masu karɓa. Wannan tashar tashar ion zaɓi ce ta zaɓaɓɓe kuma tana ƙaddamar da lalata lalatawa da motsa jiki a cikin tsarin kulawa na tsakiya da na gefe.
5-HT3 mai adawa: Masu hamayyar 5-HT 3 , wadanda ba bisa ka'ida ba aka fi sani da " setrons ", rukuni ne na magungunan da ke aiki a matsayin mai karɓar rashi a mai karɓar 5-HT 3 , wani nau'in nau'in mai karɓar maganin serotonin da aka samo a ƙarshen jijiyoyin farji da kuma wasu yankuna Tare da keɓaɓɓun keɓaɓɓun alosetron da cilansetron, waɗanda ake amfani da su wajen maganin cututtukan hanji, duk masu adawa da 5-HT 3 na maganin rigakafi ne, ana amfani da su a cikin rigakafin da magani na tashin zuciya da amai. Suna da tasiri musamman wajen sarrafa tashin zuciya da amai waɗanda cutar sankara ta haifar kuma ana ɗaukarsu matsayin ma'aunin zinare don wannan dalili.
5-HT3 mai adawa: Masu hamayyar 5-HT 3 , wadanda ba bisa ka'ida ba aka fi sani da " setrons ", rukuni ne na magungunan da ke aiki a matsayin mai karɓar rashi a mai karɓar 5-HT 3 , wani nau'in nau'in mai karɓar maganin serotonin da aka samo a ƙarshen jijiyoyin farji da kuma wasu yankuna Tare da keɓaɓɓun keɓaɓɓun alosetron da cilansetron, waɗanda ake amfani da su wajen maganin cututtukan hanji, duk masu adawa da 5-HT 3 na maganin rigakafi ne, ana amfani da su a cikin rigakafin da magani na tashin zuciya da amai. Suna da tasiri musamman wajen sarrafa tashin zuciya da amai waɗanda cutar sankara ta haifar kuma ana ɗaukarsu matsayin ma'aunin zinare don wannan dalili.
5-HT3 mai karɓa: Mai karɓa na 5-HT 3 na mamakin gidan Cys-loop ne na tashar tashoshin haɗin gwanon jini (LGICs) sabili da haka ya bambanta da tsari da aiki daga dukkan sauran masu karɓar 5-HT (5-hydroxytryptamine, ko serotonin) waɗanda ke da haɗin G-haɗe masu karɓa. Wannan tashar tashar ion zaɓi ce ta zaɓaɓɓe kuma tana ƙaddamar da lalata lalatawa da motsa jiki a cikin tsarin kulawa na tsakiya da na gefe.
5-HT3 mai adawa: Masu hamayyar 5-HT 3 , wadanda ba bisa ka'ida ba aka fi sani da " setrons ", rukuni ne na magungunan da ke aiki a matsayin mai karɓar rashi a mai karɓar 5-HT 3 , wani nau'in nau'in mai karɓar maganin serotonin da aka samo a ƙarshen jijiyoyin farji da kuma wasu yankuna Tare da keɓaɓɓun keɓaɓɓun alosetron da cilansetron, waɗanda ake amfani da su wajen maganin cututtukan hanji, duk masu adawa da 5-HT 3 na maganin rigakafi ne, ana amfani da su a cikin rigakafin da magani na tashin zuciya da amai. Suna da tasiri musamman wajen sarrafa tashin zuciya da amai waɗanda cutar sankara ta haifar kuma ana ɗaukarsu matsayin ma'aunin zinare don wannan dalili.
5-HT3 mai adawa: Masu hamayyar 5-HT 3 , wadanda ba bisa ka'ida ba aka fi sani da " setrons ", rukuni ne na magungunan da ke aiki a matsayin mai karɓar rashi a mai karɓar 5-HT 3 , wani nau'in nau'in mai karɓar maganin serotonin da aka samo a ƙarshen jijiyoyin farji da kuma wasu yankuna Tare da keɓaɓɓun keɓaɓɓun alosetron da cilansetron, waɗanda ake amfani da su wajen maganin cututtukan hanji, duk masu adawa da 5-HT 3 na maganin rigakafi ne, ana amfani da su a cikin rigakafin da magani na tashin zuciya da amai. Suna da tasiri musamman wajen sarrafa tashin zuciya da amai waɗanda cutar sankara ta haifar kuma ana ɗaukarsu matsayin ma'aunin zinare don wannan dalili.
5-HT4 mai karɓa: 5-Hydroxytryptamine mai karɓar rashi 4 furotin ne wanda a cikin mutane aka sanya shi ta hanyar kwayar halittar HTR4 .
5-HT4 mai karɓa: 5-Hydroxytryptamine mai karɓar rashi 4 furotin ne wanda a cikin mutane aka sanya shi ta hanyar kwayar halittar HTR4 .
5-HT4 mai karɓa: 5-Hydroxytryptamine mai karɓar rashi 4 furotin ne wanda a cikin mutane aka sanya shi ta hanyar kwayar halittar HTR4 .
Serotonin agonist mai karɓa: Agonist mai karɓa na serotonin shine agonist na ɗaya ko fiye masu karɓar maganin serotonin. Suna kunna masu karɓar maganin serotonin ta hanyar kama da na serotonin, neurotransmitter da hormone da haɗarin haɗarin masu karɓar maganin serotonin.
5-HT4 mai karɓa: 5-Hydroxytryptamine mai karɓar rashi 4 furotin ne wanda a cikin mutane aka sanya shi ta hanyar kwayar halittar HTR4 .
5-HT5A mai karɓa: 5-Hydroxytryptamine (serotonin) mai karɓar 5A , wanda aka fi sani da HTR5A , furotin ne wanda ke jikin mutum an tsara shi ta hanyar kwayar HTR5A . Agonists da antagonists don masu karɓa na 5-HT, da kuma masu hana maganin serotonin, gabatarwa na yanzu (inganta ƙwaƙwalwa) da / ko tasirin anti-amnesic a ƙarƙashin yanayi daban-daban, kuma masu karɓar 5-HT suna da alaƙa da canje-canje na jijiyoyi.
5-HT5A mai karɓa: 5-Hydroxytryptamine (serotonin) mai karɓar 5A , wanda aka fi sani da HTR5A , furotin ne wanda ke jikin mutum an tsara shi ta hanyar kwayar HTR5A . Agonists da antagonists don masu karɓa na 5-HT, da kuma masu hana maganin serotonin, gabatarwa na yanzu (inganta ƙwaƙwalwa) da / ko tasirin anti-amnesic a ƙarƙashin yanayi daban-daban, kuma masu karɓar 5-HT suna da alaƙa da canje-canje na jijiyoyi.
5-HT5A mai karɓa: 5-Hydroxytryptamine (serotonin) mai karɓar 5A , wanda aka fi sani da HTR5A , furotin ne wanda ke jikin mutum an tsara shi ta hanyar kwayar HTR5A . Agonists da antagonists don masu karɓa na 5-HT, da kuma masu hana maganin serotonin, gabatarwa na yanzu (inganta ƙwaƙwalwa) da / ko tasirin anti-amnesic a ƙarƙashin yanayi daban-daban, kuma masu karɓar 5-HT suna da alaƙa da canje-canje na jijiyoyi.
5-HT5B mai karɓa: Mai karɓar 5-HT 5B furotin ne mai karɓar 5-HT da kuma kwayar halittar da ke kewaya ta. Ana samun furotin a cikin beraye, amma ba a cikin mutane ba, saboda tsayar da kodin a cikin jerin lambar kwayar halitta suna hana kwayar halittar bayyana furotin mai aiki. An yi imanin cewa an maye gurbin aikin mai karɓar 5-HT 5B a cikin ɗan adam ta hanyar wasu ƙananan ƙananan ƙananan masu karɓar 5-HT. Mai karɓar 5-HT 5B shine mai karɓar G mai haɗin protein. 5-HT 5B mai karɓar mRNA an bayyana shi da farko a cikin habenula, hippocampus da zaitun mara kyau na ƙwarin bera. Sanannun masu gwagwarmaya don 5-HT 5B sun haɗa da ergotamine da LSD. Sanannun abokan gaba sun haɗa da methiothepin.
5-HT5A mai karɓa: 5-Hydroxytryptamine (serotonin) mai karɓar 5A , wanda aka fi sani da HTR5A , furotin ne wanda ke jikin mutum an tsara shi ta hanyar kwayar HTR5A . Agonists da antagonists don masu karɓa na 5-HT, da kuma masu hana maganin serotonin, gabatarwa na yanzu (inganta ƙwaƙwalwa) da / ko tasirin anti-amnesic a ƙarƙashin yanayi daban-daban, kuma masu karɓar 5-HT suna da alaƙa da canje-canje na jijiyoyi.
5-HT6 mai karɓa: Mai karɓar 5HT 6 ƙananan nau'in mai karɓar 5HT ne wanda ke ɗauke da kwayar cutar kwayar cutar serotonin (5-hydroxytryptamine, 5HT). Yana da mai karɓar furotin na G (GPCR) wanda yake haɗe da G s kuma yana yin musayar saurin motsa jiki. HTR6 yana nuna tsarin kwayar halittar mutum don mai karɓa.
5-HT6 mai karɓa: Mai karɓar 5HT 6 ƙananan nau'in mai karɓar 5HT ne wanda ke ɗauke da kwayar cutar kwayar cutar serotonin (5-hydroxytryptamine, 5HT). Yana da mai karɓar furotin na G (GPCR) wanda yake haɗe da G s kuma yana yin musayar saurin motsa jiki. HTR6 yana nuna tsarin kwayar halittar mutum don mai karɓa.
5-HT7 mai karɓa: Mai karɓar 5-HT 7 memba ne na GPCR superfamily na masu karɓar sel kuma ana amfani da shi ta hanyar serotonin (5-hydroxytryptamine, 5-HT) Mai karɓar 5-HT 7 an haɗa shi da G s (yana ƙarfafa samar da samfuran. kwayar siginar siginar cikin cikin CAMP) kuma ana bayyana shi a cikin nau'ikan kyallen takarda na mutum, musamman a cikin kwakwalwa, sashin hanji, da kuma cikin jijiyoyin jini daban-daban. Wannan mai karɓa ya kasance makasudin ci gaban ƙwayoyi don maganin cututtukan asibiti da yawa. Mai karɓar mai karɓar 5-HT 7 an tsara shi ta hanyar kwayar HTR7 , wanda a cikin ɗan adam aka fassara shi zuwa nau'ikan nau'ikan nau'ikan nau'ikan nau'ikan nau'ikan nau'ikan fako 3.
5-HT7 mai karɓa: Mai karɓar 5-HT 7 memba ne na GPCR superfamily na masu karɓar sel kuma ana amfani da shi ta hanyar serotonin (5-hydroxytryptamine, 5-HT) Mai karɓar 5-HT 7 an haɗa shi da G s (yana ƙarfafa samar da samfuran. kwayar siginar siginar cikin cikin CAMP) kuma ana bayyana shi a cikin nau'ikan kyallen takarda na mutum, musamman a cikin kwakwalwa, sashin hanji, da kuma cikin jijiyoyin jini daban-daban. Wannan mai karɓa ya kasance makasudin ci gaban ƙwayoyi don maganin cututtukan asibiti da yawa. Mai karɓar mai karɓar 5-HT 7 an tsara shi ta hanyar kwayar HTR7 , wanda a cikin ɗan adam aka fassara shi zuwa nau'ikan nau'ikan nau'ikan nau'ikan nau'ikan nau'ikan nau'ikan fako 3.
5-Hydroxytriptophan: 5-Hydroxytryptophan ( 5-HTP ), wanda aka fi sani da oxitriptan , amino acid ne wanda ke faruwa a halin yanzu da kuma yanayin kimiyyar sinadarai da kuma matsakaiciyar rayuwa a cikin kwayar halittar kwayar halitta ta serotonin.
Bufotenidine: Bufotenidine , wanda aka fi sani da 5-hydroxy- N , N , N -trimethyltryptammonium ( 5-HTQ ), guba ce da ke da alaƙa da bufotenin, serotonin, da sauran mayuka waɗanda ake samu a cikin dafin toads iri-iri. Yana aiki azaman mai karɓar mai karɓa na 5-HT 3 , kuma anyi amfani dashi a cikin binciken kimiyya don nazarin aikin mai karɓar 5-HT 3 , kodayake wannan amfani ya iyakance da gaskiyar cewa, a matsayin amine na quaternary, ba zai iya ba don sauƙin ƙetare shingen jini-kwakwalwa.
Serotonin jigilar kaya: Jirgin jigilar serotonin wanda aka fi sani da jigilar serotonin mai dogaro da sodium kuma mai ɗauke da dangi 6 memba 4 furotin ne wanda a cikin mutane keɓaɓɓe da kwayar SLC6A4 . SERT wani nau'in furotin ne mai jigilar jigilar jigilar jigilar kwayar halitta wanda ke jigilar serotonin daga maɓallin synaptic zuwa ga neuron mai tsinkayewa.
5-HTTLPR: 5-HTTLPR yanki ne wanda aka sake maimaita polymorphic a cikin SLC6A4 , kwayar halittar da ke lambobi ga mai safarar serotonin. Tunda aka gano polymorphism a tsakiyar shekarun 1990, an yi bincike mai zurfi, misali, dangane da cututtukan neuropsychiatric. 2006 kimiyya labarin ya bayyana cewa "sama da halayyar 300, halayyar dan adam, ilimin hada magunguna da sauran takardun kwayar halittar likita" sun yi nazarin polymorphism. Duk da yake ana tattaunawa sau da yawa a matsayin misali na hulɗar yanayin-yanayin, wannan takaddama ana ta gwagwarmaya.
5-HT1D mai karɓa: 5-hydroxytryptamine (serotonin) mai karɓar 1D , wanda aka fi sani da HTR1D , mai karɓar 5-HT ne, amma kuma yana nuna kwayar halittar mutum da ke sanya shi. 5-HT 1D yana aiki akan tsarin juyayi na tsakiya, kuma yana shafar motsi da damuwa. Hakanan yana haifar da jijiyoyin bugun jini a cikin kwakwalwa.
5-HT3 mai karɓa: Mai karɓa na 5-HT 3 na mamakin gidan Cys-loop ne na tashar tashoshin haɗin gwanon jini (LGICs) sabili da haka ya bambanta da tsari da aiki daga dukkan sauran masu karɓar 5-HT (5-hydroxytryptamine, ko serotonin) waɗanda ke da haɗin G-haɗe masu karɓa. Wannan tashar tashar ion zaɓi ce ta zaɓaɓɓe kuma tana ƙaddamar da lalata lalatawa da motsa jiki a cikin tsarin kulawa na tsakiya da na gefe.
Aralkylamine N-acetyltransferase: Aralkylamine N -acetyltransferase ( AANAT ), wanda aka fi sani da arylalkylamine N -acetyltransferase ko serotonin N -acetyltransferase (SNAT), enzyme ne wanda ke cikin aikin samar da melatonin na dare da rana, ta hanyar gyaran serotonin. Yana cikin mutane wanda aka sanya shi ta hanyar ~ 2.5 kb AANAT mai dauke da exons hudu, wanda yake kan chromosome 17q25. An fassara kwayar halitta zuwa babban enzyme 23 kDa. An kiyaye shi sosai ta hanyar juyin halitta kuma yanayin ɗan adam na furotin ya kai kashi 80 daidai da tumaki da bera AANAT. Yana da enzyme mai dogara da acetyl-CoA na dangin GCN5 na N -acetyltransferases (GNATs). Yana iya taimakawa ga cututtukan cututtukan ƙwayoyin cuta masu yawa kamar halaye masu canzawa a cikin yanayin bacci / farkawa kuma ana ci gaba da bincike tare da manufar haɓaka magunguna waɗanda ke tsara aikin AANAT.
Serotonin mai karɓar mai karɓa: Mai tayar da jijiyar serotonin , ko antagonist mai karɓa na serotonin , magani ne da ake amfani dashi don hana aikin a masu karɓar serotonin (5-HT).
5-HT mai karɓa: Masu karɓar 5-HT, masu karɓar 5-hydroxytryptamine , ko masu karɓar serotonin , ƙungiya ce ta mai karɓar furotin na G da kuma tashoshin ion da ke cikin jijiyoyin da ke cikin tsakiya da tsarin jijiyoyin jiki. Suna yin sulhuntawa da haɓakawa da hana karɓuwa. Masu karɓar maganin serotonin suna aiki ta hanyar serotonin neurotransmitter, wanda ke aiki azaman ligand ɗin su na halitta.
5-HT2C mai karɓa: Mai karɓar 5-HT 2C wani nau'in nau'i ne na mai karɓar 5-HT wanda ke ɗauke da kwayar cutar kwayar cutar serotonin (5-hydroxytryptamine, 5-HT). Yana da mai karɓar furotin G guda biyu (GPCR) wanda yake haɗe da G q / G 11 kuma yana yin musayar siginar ne. HTR2C yana nuna tsarin kwayar halittar mutum don mai karɓa, cewa a cikin mutane yana cikin ch chromosome na X. Kamar yadda maza ke da kwaya daya na kwayar halitta kuma a cikin mata daya daga cikin kwafin kwayar halitta guda biyu an danne su, polymorphisms a wannan mai karɓa na iya shafar jinsi biyu zuwa daban.
5-HT mai karɓa: Masu karɓar 5-HT, masu karɓar 5-hydroxytryptamine , ko masu karɓar serotonin , ƙungiya ce ta mai karɓar furotin na G da kuma tashoshin ion da ke cikin jijiyoyin da ke cikin tsakiya da tsarin jijiyoyin jiki. Suna yin sulhuntawa da haɓakawa da hana karɓuwa. Masu karɓar maganin serotonin suna aiki ta hanyar serotonin neurotransmitter, wanda ke aiki azaman ligand ɗin su na halitta.
5-HT mai karɓa: Masu karɓar 5-HT, masu karɓar 5-hydroxytryptamine , ko masu karɓar serotonin , ƙungiya ce ta mai karɓar furotin na G da kuma tashoshin ion da ke cikin jijiyoyin da ke cikin tsakiya da tsarin jijiyoyin jiki. Suna yin sulhuntawa da haɓakawa da hana karɓuwa. Masu karɓar maganin serotonin suna aiki ta hanyar serotonin neurotransmitter, wanda ke aiki azaman ligand ɗin su na halitta.
Serotonin mai sakin wakilai: Wani mai sakar sinadarin sirotonin ( SRA ) wani nau'in magani ne wanda ke haifar da sakin serotonin a cikin raƙuman ƙwayoyin cuta na neuronal. Mai zaɓin serotonin mai zaɓin sakewa ( SSRA ) SRA ne mai ƙarancin mahimmanci ko rashin tasiri a cikin samar da kwayar cutar neurotransmitter a wasu nau'ikan ƙwayoyin cuta na monoamine.
Serotonin mai sakin wakilai: Wani mai sakar sinadarin sirotonin ( SRA ) wani nau'in magani ne wanda ke haifar da sakin serotonin a cikin raƙuman ƙwayoyin cuta na neuronal. Mai zaɓin serotonin mai zaɓin sakewa ( SSRA ) SRA ne mai ƙarancin mahimmanci ko rashin tasiri a cikin samar da kwayar cutar neurotransmitter a wasu nau'ikan ƙwayoyin cuta na monoamine.
Ciwon Serotonin: Ciwon Serotonin ( SS ) rukuni ne na alamun da ke iya faruwa tare da amfani da wasu magungunan serotonergic ko kwayoyi. Matsayin alamun cututtuka na iya zama daga mai sauƙi zuwa mai tsanani. Kwayar cutar a lokuta masu sauki sun hada da hawan jini da saurin bugun zuciya; yawanci ba tare da zazzabi ba. Kwayar cutar a cikin tsaka-tsakin yanayi sun hada da yawan zafin jiki na jiki, tashin hankali, karin tunani, rawar jiki, zufa, daliban da suka fadada, da gudawa A cikin yanayi mai tsanani zafin jiki na iya ƙaruwa zuwa sama da 41.1 ° C (106.0 ° F). Matsalolin na iya haɗawa da kamuwa da cututtukan tsoka da yawa.
Serotonin jigilar kaya: Jirgin jigilar serotonin wanda aka fi sani da jigilar serotonin mai dogaro da sodium kuma mai ɗauke da dangi 6 memba 4 furotin ne wanda a cikin mutane keɓaɓɓe da kwayar SLC6A4 . SERT wani nau'in furotin ne mai jigilar jigilar jigilar jigilar kwayar halitta wanda ke jigilar serotonin daga maɓallin synaptic zuwa ga neuron mai tsinkayewa.
5-Kai harin Shark: 5-Headed Shark Attack wani fim ne na ban tsoro na Amurka wanda aka yi don telebijin na sci-fi na 2017 wanda Asylum ya haɗu tare da Syfy. Duk da nuna kifin kifin mai dauke da kawuna biyar, fim din shi ne kashi na uku a cikin jerin finafinai masu dauke da kai da yawa, wadanda ke bin 2-Karkashin Shark Attack da 3-Headed Shark Attack da kuma wanda ya gabata na 6-Kai Shark Attack , tare da wannan fim din da ke dauke da duka shark mai kai hudu da kai biyar.
5-Histidylcysteine ​​sulfoxide synthase: 5-Histidylcysteine ​​sulfoxide synthase shine farkon enzyme a cikin biosynthesis na ovothiol, yana haɓaka haɓakar ƙwayar cysteine ​​zuwa histidine, ya zama 5-histidylcysteine ​​sulfoxide. Ana samun enzyme a cikin Trypanosomes, inda ƙari kuma yana da SAM dogaro da methyl transferase, wanda ke ƙara ƙungiyar methyl zuwa N1.
5-Energy makamashi: Makamashi 5-hour makamashi ne na Amurka wanda aka ƙera shi ta Rayuwar Muhimman abubuwa LLC. Shugaba Manoj Bhargava ne ya kafa kamfanin kuma aka fara shi a shekarar 2004.
5-Hour Energy (ƙungiyar kekuna): 5-Hour Energy wani rukunin kekuna ne na UCI wanda aka kafa a shekarar 2009 a Amurka.
5-hour Makamashi 200: 5-hour Energy 200 na iya komawa zuwa tseren NASCAR masu zuwa: 5-Energy Energy 200, Tsarin bazara / farkon bazara Tsarin Gasar Kasa a Dover International Speedway da aka gudanar tsakanin 2011 da 2013 5-hour Energy 200, Faduwar Gasar Kasa-Da-Kasa a Dover International Speedway da aka fara farawa 2013
Makamashi 5-Hour 250: 5-Hour Energy 250 ya kasance tseren NASCAR na wideasa na heldasa wanda aka gudanar a World Wide Technology Raceway a Gateway a Madison, Illinois.
Juglone: Juglone , wanda ake kira 5-hydroxy-1,4-naphthalenedione (IUPAC) wani sinadari ne wanda yake dauke da tsarin kwayoyin C 10 H 6 O 3 . A masana'antar abinci, ana kiran juglone da suna CI Natural Brown 7 da CI 75500 . Ba shi narkewa cikin benzene amma yana narkewa cikin dioxane, daga inda yake kara haske kamar allurar rawaya. Isomer ne naoneone, wanda shine gurɓataccen launi a cikin ganyen henna.
5-Hydroxy-2 (5H) -furanone: 5-Hydroxy-2 (5 H ) -furanone furanni ne wanda aka samo shi daga hadawan abu na furfural ta hanyar amfani da sinadarin oxygen. Ana yin wannan aikin hada-hada a gaba daya a cikin methanol ko ethanol tare da mai lura da hankali kamar methylene blue ko Rose bengal. Tsarin wannan aikin an nuna shi azaman ƙasa.
Eugenin: Eugenin wani abu ne wanda ya samo asali daga chromone, wani sinadari ne wanda aka samu a cikin cloves. Hakanan yana ɗaya daga cikin mahaɗan da ke haifar da ɗaci a cikin karas.
Eugenin: Eugenin wani abu ne wanda ya samo asali daga chromone, wani sinadari ne wanda aka samu a cikin cloves. Hakanan yana ɗaya daga cikin mahaɗan da ke haifar da ɗaci a cikin karas.
Fasaha: Techtochrysin wani sinadari ne mai hade da abubuwa. Yana da flavone na O-methylated, flavonoid wanda aka keɓe daga Prunus cerasus , ɗanɗano mai tsami, tsire-tsire na asalin Turai da kudu maso yamma na Asiya.
Bufotenin: Bufotenin wani samfurin kwayar halitta ne wanda yake da alaƙa da serotonin. Yana da wani alkaloid da aka samo a wasu nau'in toads, namomin kaza da tsire-tsire mafi girma.
Alpha-Methylserotonin: α-Methylserotonin ( αMS ), wanda aka fi sani da α-methyl-5-hydroxytryptamine ( α-methyl-5-HT ) ko 5-hydroxy-α-methyltryptamine ( 5-HO-αMT ), ƙaddara ce ta gwaji da ke da alaƙa da neurotransmitter serotonin (5-HT). Yana aiki azaman mai zaɓin mai karɓar maganin serotonin kuma an yi amfani dashi sosai a cikin binciken kimiyya don nazarin aikin tsarin serotonin.
Serotonin: Serotonin ko 5-hydroxytryptamine ( 5-HT ) ƙwararren ƙwayar ƙwayar ƙwayar cuta ce. Ayyukanta na ilimin halittu suna da rikitarwa kuma suna da fuskoki da yawa, yanayin canza yanayin yanayi, cognition, lada, ilmantarwa, ƙwaƙwalwar ajiya, da yawancin hanyoyin ilimin lissafi kamar amai da vasoconstriction.
5-Hydroxycytosine: 5-Hydroxycytosine sigar oxidized ne na cytosine wanda ke haɗuwa da ƙaruwa mai yawa na C zuwa maye gurbi na T, tare da wasu canje-canje C zuwa G. Ba ya gurgunta kwayar DNA kuma ana iya wuce shi ta hanyar sauye-sauyen DNA polymerases.
5-Hydroxyeicosanoid dehidrogenase: 5-Hydroxyeicosanoid dehydrogenase ( 5-HEDH ) ko kuma mafi tsari, nicotinamide adenine dinucleotide phosphate (NADP + ) -dependent dehydrogenase, enzyme ne wanda ke sarrafa kayan eicosanoid na arachidonate 5-lipoxygenase (5-LOX), 5 ( S ) -hydro -6 S , 8 Z , 11 Z , 14 Z -eicosatetraenoic acid (watau 5- ( S ) -HETE; duba 5-HETE) zuwa analog na 5-keto, 5-oxo-eicosatetraenoic acid (watau 5-oxo-6 S , 8 Z , 11 Z , 14 Z -eicosatetraenoic acid ko 5-oxo-ETE). Hakanan yana aiki a cikin shugabanci na baya, yana canza 5-oxo-ETE zuwa 5 ( S ) -HETE. Tunda 5-oxo-ETE yafi 30-100-ƙarfi fiye da 5 ( S ) -HETE a cikin nau'ikan ƙwayoyin halitta masu ƙarfi, 5-HEDH ana ɗaukarsa azaman mai tsarawa da tallata 5 ( S ) HETE kuma ta haka 5-LOX yayi tasiri akan cell aiki. Kodayake an kimanta 5-HEDH a cikin ɗakunan ƙwayoyin cuta masu ɗimbin yawa kuma a cikin shirye-shiryen ɗanyen gurɓataccen abu, har yanzu ba a kimanta shi ba game da tsarinta, don kwayar halittarta, a tsarkakakke; haka kuma, yawancin karatun akansa an gudanar dasu ne cikin kyallen takarda na mutum.
5-Hydroxyeicosatetraenoic acid: 5-Hydroxyeicosatetraenoic acid eicosanoid ne, watau na narkar da sinadarin arachidonic acid. An samar da shi ta nau'ikan kwayar halitta daban-daban a cikin mutane da sauran nau'ikan dabbobi. Wadannan kwayoyin zasu iya inganta 5 ( S ) -HETE zuwa 5-oxo-eicosatetraenoic acid (5-oxo-ETE), 5 ( S ), 15 ( S ) -dihydroxyeicosatetraenoic acid, ko 5-oxo-15-hydroxyeicosatetraenoic acid .
5-Hydroxyeicosatetraenoic acid: 5-Hydroxyeicosatetraenoic acid eicosanoid ne, watau na narkar da sinadarin arachidonic acid. An samar da shi ta nau'ikan kwayar halitta daban-daban a cikin mutane da sauran nau'ikan dabbobi. Wadannan kwayoyin zasu iya inganta 5 ( S ) -HETE zuwa 5-oxo-eicosatetraenoic acid (5-oxo-ETE), 5 ( S ), 15 ( S ) -dihydroxyeicosatetraenoic acid, ko 5-oxo-15-hydroxyeicosatetraenoic acid .
5-Hydroxyeicosatetraenoic acid: 5-Hydroxyeicosatetraenoic acid eicosanoid ne, watau na narkar da sinadarin arachidonic acid. An samar da shi ta nau'ikan kwayar halitta daban-daban a cikin mutane da sauran nau'ikan dabbobi. Wadannan kwayoyin zasu iya inganta 5 ( S ) -HETE zuwa 5-oxo-eicosatetraenoic acid (5-oxo-ETE), 5 ( S ), 15 ( S ) -dihydroxyeicosatetraenoic acid, ko 5-oxo-15-hydroxyeicosatetraenoic acid .
5-Hydroxyferulic acid: 5-Hydroxyferulic acid shine hydroxycinnamic acid.
5-Hydroxyhydantoin: 5-Hydroxyhydantoin shine samfurin samfurin abu mai kwalliya na 2xy-deoxycytidine. Idan ba a gyara ba, ana iya sarrafa shi ta hanyar polymerases ta DNA wanda ke haifar da hanyoyin mutagenic.
5-Hydroxyeicosatetraenoic acid: 5-Hydroxyeicosatetraenoic acid eicosanoid ne, watau na narkar da sinadarin arachidonic acid. An samar da shi ta nau'ikan kwayar halitta daban-daban a cikin mutane da sauran nau'ikan dabbobi. Wadannan kwayoyin zasu iya inganta 5 ( S ) -HETE zuwa 5-oxo-eicosatetraenoic acid (5-oxo-ETE), 5 ( S ), 15 ( S ) -dihydroxyeicosatetraenoic acid, ko 5-oxo-15-hydroxyeicosatetraenoic acid .
5-Hydroxyeicosatetraenoic acid: 5-Hydroxyeicosatetraenoic acid eicosanoid ne, watau na narkar da sinadarin arachidonic acid. An samar da shi ta nau'ikan kwayar halitta daban-daban a cikin mutane da sauran nau'ikan dabbobi. Wadannan kwayoyin zasu iya inganta 5 ( S ) -HETE zuwa 5-oxo-eicosatetraenoic acid (5-oxo-ETE), 5 ( S ), 15 ( S ) -dihydroxyeicosatetraenoic acid, ko 5-oxo-15-hydroxyeicosatetraenoic acid .
5-Hydroxyindoleacetic acid: 5-Hydroxyindoleacetic acid (5-HIAA) shine babban haɓakar serotonin. A cikin binciken sinadarai na samfurin fitsari, ana amfani da 5-HIAA don tantance matakan serotonin a jiki.
5-Hydroxyindoleacetic acid: 5-Hydroxyindoleacetic acid (5-HIAA) shine babban haɓakar serotonin. A cikin binciken sinadarai na samfurin fitsari, ana amfani da 5-HIAA don tantance matakan serotonin a jiki.
5-Hydroxyisourate: 5-Hydroxyisourate kwayoyin ne tare da dabara na C 5 H 4 N 4 O 4 kuma nauyin kwayoyin na 184.110 g / mol. Samfurin hadawan abu ne na uric acid ta urate oxidase.
5-Hydroxymaltol: 5-Hydroxymaltol , wanda aka samu daga maltol, wani sinadari ne wanda za'a sameshi a Penicillium echinulatum . Hakanan ana samun sa a cikin itacen oak mai ƙayatarwa kuma a cikin honeys daga shuɗin gumin da akwatin rawaya.
Hydioxymethylfurfural: Hydroxymethylfurfural (HMF), kuma 5- (hydroxymethyl) furfural, wani mahaɗin ne wanda aka samar dashi ta hanyar rashin ruwa na wasu sugars. Yana da farin mai narkarda mai narkewa wanda yake narkewa sosai a cikin ruwa da ƙwayoyin halitta. Kwayar tana dauke da zobe na furan, wanda ya hada da aldehyde da kungiyoyin aikin barasa.
5-Hydroxymethylcytosine: 5-Hydroxymethylcytosine (5hmC) shine tushen DNA pyrimidine nitrogen wanda aka samo daga cytosine. Yana da mahimmanci a cikin epigenetics, saboda ƙungiyar hydroxymethyl akan cytosine na iya yuyar kunna jinsi ya kunna. An fara ganinta a cikin kwayoyin cuta a shekarar 1952. Amma, a shekarar 2009 an gano tana da yalwar a kwakwalwar mutum da linzamin kwamfuta, haka kuma a cikin kwayar halittar mahaifar tayi. A cikin dabbobi masu shayarwa, ana iya samar dashi ta hanyar hada abubuwa 5-methylcytosine, wani dauki da aka samu tsakanin TET enzymes. Tsarin kwayoyin shine C 5 H 7 N 3 O 2 .
Hydioxymethylfurfural: Hydroxymethylfurfural (HMF), kuma 5- (hydroxymethyl) furfural, wani mahaɗin ne wanda aka samar dashi ta hanyar rashin ruwa na wasu sugars. Yana da farin mai narkarda mai narkewa wanda yake narkewa sosai a cikin ruwa da ƙwayoyin halitta. Kwayar tana dauke da zobe na furan, wanda ya hada da aldehyde da kungiyoyin aikin barasa.
Juglone: Juglone , wanda ake kira 5-hydroxy-1,4-naphthalenedione (IUPAC) wani sinadari ne wanda yake dauke da tsarin kwayoyin C 10 H 6 O 3 . A masana'antar abinci, ana kiran juglone da suna CI Natural Brown 7 da CI 75500 . Ba shi narkewa cikin benzene amma yana narkewa cikin dioxane, daga inda yake kara haske kamar allurar rawaya. Isomer ne naoneone, wanda shine gurɓataccen launi a cikin ganyen henna.
Serotonin: Serotonin ko 5-hydroxytryptamine ( 5-HT ) ƙwararren ƙwayar ƙwayar ƙwayar cuta ce. Ayyukanta na ilimin halittu suna da rikitarwa kuma suna da fuskoki da yawa, yanayin canza yanayin yanayi, cognition, lada, ilmantarwa, ƙwaƙwalwar ajiya, da yawancin hanyoyin ilimin lissafi kamar amai da vasoconstriction.
5-HT mai karɓa: Masu karɓar 5-HT, masu karɓar 5-hydroxytryptamine , ko masu karɓar serotonin , ƙungiya ce ta mai karɓar furotin na G da kuma tashoshin ion da ke cikin jijiyoyin da ke cikin tsakiya da tsarin jijiyoyin jiki. Suna yin sulhuntawa da haɓakawa da hana karɓuwa. Masu karɓar maganin serotonin suna aiki ta hanyar serotonin neurotransmitter, wanda ke aiki azaman ligand ɗin su na halitta.
5-Hydroxytriptophan: 5-Hydroxytryptophan ( 5-HTP ), wanda aka fi sani da oxitriptan , amino acid ne wanda ke faruwa a halin yanzu da kuma yanayin kimiyyar sinadarai da kuma matsakaiciyar rayuwa a cikin kwayar halittar kwayar halitta ta serotonin.
5-Hydroxyuracil: 5-Hydroxyuracil wani nau'ine ne na sikesine wanda aka sanya shi ta iska ta hanyar lalata sinadarai ta hanyar nau'in oxygen mai amsa sigina. Ba ya gurbata kwayar DNA kuma ana kewayarsa ta hanyar kwayar halittar kwayar halitta ta DNA. Zai iya yin kuskure ga adenine kuma yana iya canzawa.
5I: 5I ko 5-Zan iya koma zuwa: Lambar IATA na Air G, wanda ake kira Transair Georgia Amos-5i, tauraron dan adam na AsiaSat 2 SSH 5I (WA), duba Hanyar Jihar Washington 510
5-BA-R91150: 5-I-R91150 wani fili ne wanda yake aiki a matsayin mai tsayayyar mai karɓa na 5-HT 2A masu karɓa . Babban aikin shi shine iodine-123 wanda aka sanya wa radiyo, wanda za'a iya amfani da shi a cikin binciken SPECT a cikin binciken kwayar halittar dan adam, don nazarin yadda ake rarraba mai karba 5-HT 2A a cikin kwakwalwa, misali game da jima'i da shekaru da a cikin manya da cutar Asperger ko cutar Alzheimer.
5-IAI: 5-Iodo-2-aminoindane ( 5-IAI ) magani ne wanda yake aiki azaman wakilin sakewa na serotonin, norepinephrine, da dopamine. An haɓaka shi a cikin 1990s ta ƙungiyar da David E. Nichols ya jagoranta a Jami'ar Purdue. 5-IAI ya cika maye gurbin MDMA a cikin rodents kuma yana da mahimmancin entactogen cikin mutane. Sabanin abubuwan da ke tattare da aminoindane kamar MDAI da MMAI, 5-IAI yana haifar da cututtukan siratonergic a cikin beraye, amma ba shi da guba sosai fiye da wanda yake daidai da piano na amphetamine, tare da ɓarnar da aka gani da ta kai ƙimar lissafi.
5-IT: 5- (2-Aminopropyl) indole yana da indole da kuma samfurin phenethylamine tare da tasirin empathogenic. Albert Hofmann ne ya fara ba da rahoton shirya shi a cikin 1962. Magunguna ne mai ƙira wanda aka siyar da shi a bayyane a matsayin magungunan nishaɗi ta masu siyar da layi tun daga 2011.
5-Inch Gyara Jirgin Sama na Jirgin Sama: Jirgin roka mai Inci 5-Forward Firing Aircraft Roket ko FFAR roka ce ta Ba'amurke da aka haɓaka yayin Yaƙin Duniya na II don kai hari daga jiragen sama akan ƙasa da maƙasudin jirgin.
5-Inch Gyara Jirgin Sama na Jirgin Sama: Jirgin roka mai Inci 5-Forward Firing Aircraft Roket ko FFAR roka ce ta Ba'amurke da aka haɓaka yayin Yaƙin Duniya na II don kai hari daga jiragen sama akan ƙasa da maƙasudin jirgin.
5-APDI: 5- (2-Aminopropyl) -2,3-dihydro-1 H -indene ( 5-APDI ), wanda aka fi sani da indanylaminopropane ( IAP ), IAP (psychedelic), 2-API (2-aminopropylindane), indanametamine, kuma, ba daidai ba, kamar indanylamphetamine , entactogen ne kuma magungunan ƙwayoyi ne na dangin amphetamine. Masu siyarwa ta yanar gizo sun siyar dashi ta hanyar yanar gizo kuma an gamu da shi azaman magani mai ƙira tun 2003, amma shahararsa da wadatar sa sun ragu a recentan shekarun nan.
5-IAI: 5-Iodo-2-aminoindane ( 5-IAI ) magani ne wanda yake aiki azaman wakilin sakewa na serotonin, norepinephrine, da dopamine. An haɓaka shi a cikin 1990s ta ƙungiyar da David E. Nichols ya jagoranta a Jami'ar Purdue. 5-IAI ya cika maye gurbin MDMA a cikin rodents kuma yana da mahimmancin entactogen cikin mutane. Sabanin abubuwan da ke tattare da aminoindane kamar MDAI da MMAI, 5-IAI yana haifar da cututtukan siratonergic a cikin beraye, amma ba shi da guba sosai fiye da wanda yake daidai da piano na amphetamine, tare da ɓarnar da aka gani da ta kai ƙimar lissafi.
5-IAI: 5-Iodo-2-aminoindane ( 5-IAI ) magani ne wanda yake aiki azaman wakilin sakewa na serotonin, norepinephrine, da dopamine. An haɓaka shi a cikin 1990s ta ƙungiyar da David E. Nichols ya jagoranta a Jami'ar Purdue. 5-IAI ya cika maye gurbin MDMA a cikin rodents kuma yana da mahimmancin entactogen cikin mutane. Sabanin abubuwan da ke tattare da aminoindane kamar MDAI da MMAI, 5-IAI yana haifar da cututtukan siratonergic a cikin beraye, amma ba shi da guba sosai fiye da wanda yake daidai da piano na amphetamine, tare da ɓarnar da aka gani da ta kai ƙimar lissafi.
5-IAI: 5-Iodo-2-aminoindane ( 5-IAI ) magani ne wanda yake aiki azaman wakilin sakewa na serotonin, norepinephrine, da dopamine. An haɓaka shi a cikin 1990s ta ƙungiyar da David E. Nichols ya jagoranta a Jami'ar Purdue. 5-IAI ya cika maye gurbin MDMA a cikin rodents kuma yana da mahimmancin entactogen cikin mutane. Sabanin abubuwan da ke tattare da aminoindane kamar MDAI da MMAI, 5-IAI yana haifar da cututtukan siratonergic a cikin beraye, amma ba shi da guba sosai fiye da wanda yake daidai da piano na amphetamine, tare da ɓarnar da aka gani da ta kai ƙimar lissafi.
5-Iodowillardiine: 5-Iodowillardiine shine agonist mai zaɓa don mai karɓar kainate, tare da iyakantaccen sakamako a mai karɓar AMPA. Yana da zaɓi don masu karɓar kainate waɗanda aka haɗa da ƙananan rukunin GluR5. Yana da neurotoxin mai saurin motsa jiki a cikin rayuwa , amma ya tabbatar da matukar amfani don nuna ƙarancin ƙananan abubuwa da aiki na masu karɓar kainate daban-daban a cikin kwakwalwa da laka.
5J: 5J ko 5-J na iya komawa zuwa: Cebu Pacific, kamfanin jirgin sama na Philippines 5J injuna, samfurin Škoda Fabia Secondary State Highway 5J, tsohon suna don Washington State Route 702 Inyaddarar Daleks , Doctor 1979 mai serial
5K: 5K ko 5-K na iya komawa zuwa: 5K ƙuduri, ƙudurin nuni tare da ƙudurin kwance a kan tsari na pixels 5,000 Gnome-Rhône 5K, injin jirgin sama mai walƙiya Mita 5000, taron tsere ne mai nisa a cikin hanya da filin 5K gudu, gasar tsere mai nisa mai nisa Barka dai Fly (kamfanin jirgin sama) Ks biyar a cikin Sikhism, abubuwa biyar da aka umarci Khalsa Sikhs su sa a kowane lokaci Sander Kleinenberg Ya gabatar da kundin 5K , 2010 na Dutch DJ Sander Kleinenberg Nightmare of Eden , a 1979 Doctor Who serial
5K gudu: Gudun 5K shine gasa mai tsayin hanya mai nisa akan nisan kilomita biyar (3.107 mi). Hakanan ana magana dashi azaman tsere na hanya 5K , kilomita 5 , ko kuma sau 5K kawai, shine mafi gajarta daga mafi yawan hanyoyin nesa masu saurin gudu. Yawanci ana rarrabe shi daga taron tseren mita 5000 ta hanyar faɗin nisan kilomita, maimakon mita.
5L: 5L ko 5-L na iya koma zuwa:
Arachidonate 5-lipoxygenase: Arachidonate 5-lipoxygenase , wanda aka fi sani da ALOX5 , 5-lipoxygenase , 5-LOX , ko 5-LO , enzyme ne wanda ba shi da sinadarin baƙin ƙarfe wanda a cikin mutane keɓaɓɓe da kwayar ta ALOX5 . Arachidonate 5-lipoxygenase memba ne na gidan lipoxygenase na enzymes. Yana canza mahimmin mai mai (EFA) a cikin leukotrienes da kewayon sauran kayan aiki masu ilimin halitta. ALOX5 shine manufa ta yanzu don magance magunguna a cikin cututtuka da yawa.
Arachidonate 5-lipoxygenase: Arachidonate 5-lipoxygenase , wanda aka fi sani da ALOX5 , 5-lipoxygenase , 5-LOX , ko 5-LO , enzyme ne wanda ba shi da sinadarin baƙin ƙarfe wanda a cikin mutane keɓaɓɓe da kwayar ta ALOX5 . Arachidonate 5-lipoxygenase memba ne na gidan lipoxygenase na enzymes. Yana canza mahimmin mai mai (EFA) a cikin leukotrienes da kewayon sauran kayan aiki masu ilimin halitta. ALOX5 shine manufa ta yanzu don magance magunguna a cikin cututtuka da yawa.
Arachidonate 5-lipoxygenase mai hanawa: Masu hanawa na 5-lipoxygenase na Arachidonate mahadi ne wanda ke jinkirta ko dakatar da aikin enzyme na arachidonate 5-lipoxygenase, wanda ke da alhakin samar da leukotrienes mai kumburi. Yawan yin leukotrienes shine babban dalilin kumburi a cikin asma, rashin lafiyar rhinitis, da osteoarthritis.
Arachidonate 5-lipoxygenase: Arachidonate 5-lipoxygenase , wanda aka fi sani da ALOX5 , 5-lipoxygenase , 5-LOX , ko 5-LO , enzyme ne wanda ba shi da sinadarin baƙin ƙarfe wanda a cikin mutane keɓaɓɓe da kwayar ta ALOX5 . Arachidonate 5-lipoxygenase memba ne na gidan lipoxygenase na enzymes. Yana canza mahimmin mai mai (EFA) a cikin leukotrienes da kewayon sauran kayan aiki masu ilimin halitta. ALOX5 shine manufa ta yanzu don magance magunguna a cikin cututtuka da yawa.
5 (Sabis ɗin Jirgin karkashin Kasa na New York): 5 Lexington Avenue Express sabis ne mai saurin wucewa a cikin A Division na Subway City New York. Alamar hanyarta, ko "harsashi", launin kore ne mai kalar apple tunda yana amfani da Layin IRT Lexington Avenue a Manhattan.
5 (Sabis ɗin Jirgin karkashin Kasa na New York): 5 Lexington Avenue Express sabis ne mai saurin wucewa a cikin A Division na Subway City New York. Alamar hanyarta, ko "harsashi", launin kore ne mai kalar apple tunda yana amfani da Layin IRT Lexington Avenue a Manhattan.
Arachidonate 5-lipoxygenase: Arachidonate 5-lipoxygenase , wanda aka fi sani da ALOX5 , 5-lipoxygenase , 5-LOX , ko 5-LO , enzyme ne wanda ba shi da sinadarin baƙin ƙarfe wanda a cikin mutane keɓaɓɓe da kwayar ta ALOX5 . Arachidonate 5-lipoxygenase memba ne na gidan lipoxygenase na enzymes. Yana canza mahimmin mai mai (EFA) a cikin leukotrienes da kewayon sauran kayan aiki masu ilimin halitta. ALOX5 shine manufa ta yanzu don magance magunguna a cikin cututtuka da yawa.
5-lipoxygenase-kunna furotin: Arachidonate 5-lipoxygenase-activating protein wanda aka fi sani da 5-lipoxygenase mai kunna protein , ko FLAP , furotin ne wanda yake cikin mutane an tsara shi ta hanyar kwayar ALOX5AP .
5-lipoxygenase-kunna furotin: Arachidonate 5-lipoxygenase-activating protein wanda aka fi sani da 5-lipoxygenase mai kunna protein , ko FLAP , furotin ne wanda yake cikin mutane an tsara shi ta hanyar kwayar ALOX5AP .
5M: 5M ko 5-M na iya komawa zuwa: Misalin 5M, samfurin gyara matsala da tsarin haɗari da aka yi amfani dashi don amincin jirgin sama Sibaviatrans, tsohon kamfanin jirgin sama 5M, injin Toyota M 5M, samfurin HP LaserJet 5 Shada , likita ne wanda ba a karasa shi ba Wanda ya cika
5-MBPB: 5-MBPB samfurin amfetamine ne wanda ke da alaƙa da tsarin MDMA kuma an siyar dashi azaman magani mai ƙira. Ana iya bayyana shi azaman analog ɗin benzofuran-5-yl na MBDB ko mahaɗin butanamine na 5-MAPB, kuma mahimmin tsari ne na 5-EAPB da 6-EAPB. Rahotannin Anecdotal sun nuna cewa an sayar da wannan fili a matsayin likitan zane a kasashe daban-daban na Turai tun a farkon 2015, amma an gano asalin farko a cikin watan Disambar 2015 ta wani dakin bincike a Slovenia.
5-MAPB: 5-MAPB magani ne mai tsara kayan kwalliya irin na MDMA a cikin tsarin sa da tasirin sa.
5-MAPDB: 5-MAPDB ( 1- (2,3-dihydrobenzofuran-5-yl) -N-methylpropan-2-amine ) wani sinadari ne wanda yake aiki azaman magani na entactogenic. Yana da alaƙar tsari da magunguna kamar 5-APDB da 5-MAPB, waɗanda ke da irin wannan tasirin ga MDMA kuma an yi amfani da su azaman magunguna na nishaɗi. 5-MAPDB anyi nazari don tantance aikin sa na magani, kuma an gano shi mai sakin siratonin ne mai sauƙin zaɓi, kodayake tare da ayyuka marasa ƙarfi kamar mai sakin wasu nau'ikan monoamines da 5-HT 2 mai karɓar rawanin dangi, kama da tsofaffin mahaɗan kamar 5- APDB.